Directory · 2026
Active Radiopharmaceutical Developers
151
active developers
20
countries
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theranostic / therapeutic / diagnostic
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Showing 151 of 151
| What they develop | Expand | |||
|---|---|---|---|---|
3B Pharmaceuticals | Develops peptide-targeted radionuclide therapeutics and FAP-targeting radioligands primarily through out-licensing to larger partners | Berlin, Germany | Dx + Tx | |
3D Medicines | Shanghai-listed biopharma (688435.SH) with RDC/radioligand pipeline including Lu-177-PSMA-3D1015 in clinical development for metastatic castration-resistant prostate cancer; primarily an ADC and immuno-oncology company expanding into radiopharmaceuticals | Shanghai, China | Therapeutic | |
AB-RayBio | Early-stage developer of targeted radiopharmaceuticals with α- and β-nuclide programs; eight in-research pipelines including pan-solid-tumor programs | Hangzhou, China | Dx + Tx | |
Abdera Therapeutics | Engineers precision radiopharmaceuticals using its ROVEr™ antibody engineering platform to deliver alpha (Ac-225) or beta emitters against novel targets | South San Francisco, CA, USA | Therapeutic | |
Ablaze Pharmaceuticals | GPC-3-targeted radioligand therapy for hepatocellular carcinoma (HCC) using novel peptide drug candidates; collaboration with BMS/PeptiDream | Shanghai / Greater China, China | Therapeutic | |
ABSCINT | Develops anti-L1CAM monoclonal antibody radioconjugates for paediatric and adult solid tumours, including radiolabeled OTLC anti-L1CAM antibodies; spin-out from UCLouvain collaborating with SCK CEN on therapeutic radionuclide conjugation | Brussels, Belgium | Therapeutic | |
AC Immune | Clinical-stage biopharma developing 18F-ACI-12589, the first-ever alpha-synuclein PET tracer with first-in-human data published in Nature Communications; wholly owned diagnostic for MSA, Parkinson's disease and other synucleinopathies | Lausanne, Switzerland | Diagnostic | |
Acrotech Biopharma | Commercial oncology company holding US Zevalin radioimmunotherapy rights | East Windsor, NJ, USA | Therapeutic | |
Actinium Pharmaceuticals | NYSE-listed company with a novel preclinical Ac-225 solid-tumor program (ATNM-400) targeting a non-PSMA antigen in prostate, NSCLC, and breast cancer | New York, NY, USA | Therapeutic | |
Actithera | Precision radiopharmaceutical biotech translating covalent medicinal chemistry into next-generation radioligand therapies, with an isotope-agnostic approach | Cambridge, MA (co-HQ Oslo, Norway), USA/Norway | Therapeutic | |
Advanced Innovative Partners (AIP) | Theranostic radiopharmaceutical developer with pipeline including AIP-201, AIP-105 (rare paediatric), AIP-301, and AIP-102 across oncology, infectious disease and rare disease; holds first accelerator-produced Ac-225 patent; also provides CRO services | Boynton Beach, FL, USA | Dx + Tx | |
AdvanCell | Lead-212 targeted alpha therapy developer | Melbourne, Australia | Therapeutic | |
Affibody | Affibody molecule platform company developing HER2 radioligand therapy | Stockholm, Sweden | Dx + Tx | |
Akiram Therapeutics | Develops CD44v6-targeting radioimmunotherapy (177Lu-AKIR001) for solid tumors including head & neck and thyroid cancers; FIH Phase 1 initiated | Uppsala, Sweden | Therapeutic | |
Aktis Oncology | Miniprotein Ac-225 radioconjugate developer for solid tumors | Boston, MA, USA | Therapeutic | |
Alpha Fusion | Develops At-211-based Targeted Alpha Therapy (TAT) radiopharmaceuticals across multiple cancer indications | Osaka, Japan | Therapeutic | |
Alpha-9 Oncology | MC1R-targeted radiopharmaceutical developer for melanoma and other cancers | Vancouver, BC / Boston, MA, Canada / USA | Dx + Tx | |
AlphaGen Therapeutics | Develops next-generation Pb-212 alpha radioligand therapies using proprietary AlphaDirect Pb-212 generator technology | Shanghai, China | Therapeutic | |
Andarix Pharmaceuticals | Clinical-stage developer of Re-188-P2045 (Tozaride), a SSTR2-targeting peptide radiotherapy for neuroendocrine tumours and lung cancer, paired with 99mTc-P2045 diagnostic imaging agent; advancing through Phase 2 | Somerville, MA, USA | Dx + Tx | |
APRINOIA Therapeutics | Clinical-stage company developing tau-targeted PET diagnostic tracers (18F-APN-1607/florzolotau) and therapeutic radiopharmaceuticals for neurodegenerative diseases and brain cancers; Phase 2/3 tau PET imaging studies ongoing globally | Taipei / Suzhou, Taiwan / China | Dx + Tx | |
Archeus Technologies | RPT company developing PSMA and other targeted radioconjugates | Madison, WI, USA | Dx + Tx | |
Ariceum Therapeutics | SSTR2 antagonist and PARP-targeted radiopharmaceutical developer | Berlin, Germany | Dx + Tx | |
Artbio | Lead-212 alpha radioligand therapy developer using AlphaDirect isotope isolation | Cambridge, MA, USA | Therapeutic | |
AstraZeneca | Large pharma alpha-radioconjugate platform targeting PSMA, IGF-1R, EGFR/cMET and NTSR1 | Cambridge / Hamilton, ON, UK / Canada | Therapeutic | |
Atonco Pharma | At-211 antibody-conjugate (girentuximab × CA-IX) for non-muscle-invasive bladder cancer; FIH Phase 1 PERSEVERANCE EU trial authorized | Saint-Herblain (Nantes), France | Therapeutic | |
Bayer | Commercial alpha-emitter franchise and next-generation Ac-225 oncology pipeline | Leverkusen, Germany | Therapeutic | |
Beijing Quarkxia Technology | Chinese radionuclide therapeutic developer for bone metastases | Beijing, China | Therapeutic | |
Bicycle Therapeutics | Develops Bicycle® Radioconjugates (BRC®) using proprietary bicyclic peptides carrying ²¹²Pb (alpha) for targeted radionuclide therapy | Cambridge, UK | Dx + Tx | |
Biokin Pharmaceutical (Baili Tianheng) | Shanghai-listed biopharma (688506.SH) expanding into radiopharmaceuticals with BL-ARC001 (Lu-177 RDC) in clinical development for prostate cancer; primarily known as a leading Chinese ADC developer with BMS partnership on cadonilimab-equivalent | Chengdu, China | Therapeutic | |
Bivision Pharmaceuticals | Chinese PSMA-targeted radioligand therapy developer | Shanghai / Nanjing, China | Dx + Tx | |
Blue Earth Therapeutics | Develops an alpha-emitting radiohybrid PSMA-targeted therapeutic radiopharmaceutical (²²⁵Ac-rhPSMA-10.1) for prostate cancer | Oxford, UK | Therapeutic | |
BoomRay | Academic spin-out (WuXi AppTec + Peking University Molecular Engineering) developing first-in-class covalent targeted radioligand therapies | Suzhou, China | Dx + Tx | |
Bristol Myers Squibb | Large pharma actinium-225 radiopharmaceutical platform via RayzeBio acquisition | Princeton, NJ / San Diego, CA, USA | Therapeutic | |
C-Biomex | Korean developer of fluorine-18 PET imaging agents including 18F-FP-CIT for Parkinson's disease diagnosis and novel oncology tracers; holds KFDA approvals for multiple diagnostic radiopharmaceuticals | Seoul, South Korea | Diagnostic | |
C-Ray Therapeutics | Chengdu-based CRDMO with own therapeutic pipeline: TRC003, a PSMA-targeted radioligand in Phase 1/2 for metastatic castration-resistant prostate cancer (NCT07567521, 90 patients, sites in China); alpha-emitting RDC programs | Chengdu, China | Therapeutic | |
Cancer Targeted Technology (CTT) | PSMA-targeted theranostic developer: CTT1403 (177Lu radiotherapeutic, albumin-binding, Phase 1 complete at UCSF) paired with CTT1057 (18F PET diagnostic, Phase 1 complete); irreversible PSMA binding scaffold | Woodinville, WA, USA | Dx + Tx | |
CellBion | Korean PSMA radioligand developer | Seoul, South Korea | Therapeutic | |
Cellectar Biosciences | Clinical-stage company with a phospholipid ether (PLE) platform; CLR 125 (Auger/I-125) in Phase 1b TNBC and CLR 225, an Ac-225 alpha emitter | Florham Park, NJ, USA | Therapeutic | |
Chengdu Huasun Biotechnology | China domestic radioimmunotherapy manufacturer for hepatocellular carcinoma | Chengdu, China | Therapeutic | |
Clarity Pharmaceuticals | Copper-64/copper-67 SAR theranostic radiopharmaceutical developer | Sydney, Australia | Dx + Tx | |
Convergent Therapeutics | PSMA-targeted alpha radioantibody developer | Cambridge, MA, USA | Dx + Tx | |
Curadel Pharma | Develops fluorescence-guided surgery and targeted radiopharmaceutical agents combining near-infrared fluorescent imaging with radioligand delivery for intraoperative tumour detection and treatment | Marlborough, MA, USA | Dx + Tx | |
Curasight | uPAR-targeted theranostics company developing uTREAT radiopharmaceutical therapy | Copenhagen, Denmark | Dx + Tx | |
Curium Pharma | Large nuclear medicine company with approved legacy therapies and Phase 3 PSMA therapy | Paris, France | Therapeutic | |
CytoSite Bio | Granzyme B-targeted theranostic developer: CSB-321 PET diagnostic (Phase 1, validated in melanoma and NSCLC) paired with CSB-421 radiotherapeutic; Lantheus holds an option deal (March 2025) on the platform | Boston, MA, USA | Dx + Tx | |
Debiopharm | Swiss biopharma developing terbium-161-based radioligand therapies for cancer through its Nucleo-Oncology programme; partners with Paul Scherrer Institute and CERN/ISOLDE for Tb-161 production; advancing proprietary theranostic candidates | Lausanne, Switzerland | Therapeutic | |
Defence Therapeutics | Canadian biotech (CSE: DTC) developing Accum-enhanced radio-immunoconjugates in collaboration with Canadian Nuclear Laboratories using Ac-225 and In-111 isotopes; radiopharmaceuticals are a top development priority alongside its ADC programme | Montreal, Canada | Therapeutic | |
Diaprost | Develops h11B6, a humanised monoclonal antibody targeting hK2 (human kallikrein 2) as a radioimmunotherapy carrier for prostate cancer; paired diagnostic and therapeutic applications using different radionuclide payloads | Lund, Sweden | Dx + Tx | |
Dong Wha Pharmaceutical | Korean pharmaceutical company holding an approved Ho-166 locoregional radiotherapy product | Seoul, South Korea | Therapeutic | |
DuChemBio | Korea's leading radiopharmaceutical manufacturer with ~80% of the domestic FDG market; approved diagnostics (68Ga-PSMA-11, 18F-FES for breast cancer) and expanding into therapeutic radioligands and CDMO services | Seoul, South Korea | Dx + Tx | |
Eli Lilly | Large pharma radiopharmaceutical division with POINT-origin Lu-177 and Ac-225 assets plus new collaborations | Indianapolis, IN, USA | Therapeutic | |
Evergreen Theragnostics | Radiopharma CDMO and proprietary developer; built a GMP facility in NJ; lead diagnostic OCTEVY (EVG321, CCK2-targeting, SCLC) in Phase II | Springfield, NJ, USA | Dx + Tx | |
Faber Xintian | Develops 99mTc-H7ND, a world-first FAP-targeted SPECT/CT diagnostic radiopharmaceutical (Class 1 innovative drug); CDE clinical trial approval December 2023; Phase 1 initiated April 2024 at Fudan Zhongshan Hospital; strategic collaboration with HTA/Atom HighTech | Jiaxing, China | Diagnostic | |
Foshan Radiomedical / Beijing Jiluntai | Chinese developer and manufacturer of Sm-153-EDTMP (samarium-153 lexidronam) and other therapeutic radiopharmaceuticals for bone pain palliation in metastatic cancer; one of China's established radiopharmaceutical producers | Foshan / Beijing, China | Therapeutic | |
Fujifilm Toyama Chemical | Japan marketing authorization holder/commercial partner for Lutathera PRRT | Tokyo, Japan | Therapeutic | |
Fulian Medicine | Radionuclide drug conjugate (RDC) developer with global R&D operations spanning China, Belgium, and Germany; more than 30% of staff based in Belgium; developing nanoparticle-based radioligand therapies for solid tumours | Beijing, China | Therapeutic | |
Full-Life Technologies | Fully integrated radiotherapeutics company with an Ac-225 lead program in Phase I and multiple preclinical programs (SSTR2, c-MET, B7H3) in discovery | Suzhou / Shanghai, China (global) | Therapeutic | |
FutureChem | Developing alpha-emitter radiopharmaceuticals alongside beta-emitter programs for prostate and other cancers | Seoul, South Korea | Dx + Tx | |
Fuzionaire Theranostics | Developer of novel FAPI (fibroblast activation protein inhibitor) radioligands for theranostic cancer applications; advancing FAP-targeted imaging and therapeutic agents through clinical development | San Diego, CA, USA | Dx + Tx | |
GlyTherix | Develops glypican-1 (GPC1)-targeted radioimmunotherapy for pancreatic and other GPC1-expressing cancers; lead programme uses radiolabeled anti-GPC1 antibodies with Lu-177 and other therapeutic radionuclides | Sydney, Australia | Therapeutic | |
Grand Pharma | HK-listed biopharma with early own-pipeline radiopharma programs; GPN01530 (diagnostic FAP RDC, FIH just starting for diagnostic use) | Wuhan / Chengdu, China | Dx + Tx | |
Hexin Pharmaceuticals | Pioneer of dual-target radiopharmaceuticals simultaneously targeting integrin αvβ3 and CD13 receptor; first-in-class theranostic RDC platform | Chongqing / Beijing / Suzhou, China | Dx + Tx | |
HTA Co (Atom HighTech) | Major Chinese radiopharmaceutical developer and manufacturer under CNNC/CIRC with own clinical pipeline: F-18 Florastamin (Phase 3, prostate), Ga-68 DOTATATE (Phase 3, NETs), Lu-177 oxodotreotide (GEP-NETs); FutureChem collaboration on FC705 Lu-177 PSMA therapy; nationwide production and distribution network | Beijing, China | Dx + Tx | |
ImaginAb | Develops CD8-targeted ImmunoPET imaging agents (89Zr-Df-IAB22M2C/tozarotide) to visualise immune-cell infiltration in tumours; partnered with Bristol Myers Squibb and Roche for clinical imaging trials; lead agent in Phase 2 | Inglewood, CA, USA | Diagnostic | |
Immunome | Oncology biotech adding FAP-targeted radioligand therapy to its antibody and ADC pipeline; also advancing radiolabeled antibody programmes | Bothell, WA, USA | Therapeutic | |
imuveo | Munich-based early-stage company developing next-generation PET tracers for immune-response imaging and future radioligand therapies targeting cancer; backed by the EXIST Transfer of Research programme and Technical University of Munich | Munich, Germany | Dx + Tx | |
Iodax Pharma | Novel PSAt-Ga radiolabeling technology (in-licensed from Theranostic Solutions, Copenhagen) allowing At-211, 131I, or 68Ga labeling | Switzerland, Switzerland | Dx + Tx | |
ITM Isotope Technologies Munich | Vertically integrated radiopharma biotech with a late-clinical lead (ITM-11, Phase 3/NDA pending) and early-stage novel programs | Garching / Munich, Germany | Dx + Tx | |
Jiangsu Hengrui Pharmaceuticals | Major Chinese pharma (SHA: 600276) with emerging radioligand therapy pipeline; developing proprietary RDC candidates including PSMA- and FAP-targeted radioligands; leveraging established oncology and clinical-trial infrastructure | Lianyungang, China | Therapeutic | |
JingHe Biotech | Chinese developer of JH020002, a Lu-177 radioligand therapy for advanced prostate cancer currently in clinical trials (also registered under Bivision Pharmaceuticals in the US); early-stage RDC pipeline | China | Therapeutic | |
Johnson & Johnson | Large pharma with two Ac-225 prostate cancer radiopharmaceutical programmes | New Brunswick, NJ, USA | Therapeutic | |
Jubilant Pharmova | Large Indian pharma group with a proprietary radiopharma therapeutic pipeline including FAPI tracers in preclinical development and I-131 mIBG | Noida, India | Dx + Tx | |
Jubilant Radiopharma | Nuclear medicine company manufacturing and commercializing diagnostic and therapeutic radiopharmaceuticals | Kirkland, QC / Noida, Canada / India | Dx + Tx | |
Kelun-Biotech | Large-cap ADC company expanding into RDC; SKB107 (small-molecule RDC for bone metastases) is its first RDC program in Phase I as of Aug 2025 | Chengdu (Sichuan), China | Therapeutic | |
Lannacheng Biotechnology | Radiopharmaceutical spin-out from Dongcheng (largest listed radiopharmaceutical company); Lu-177 PSMA in Phase II; FAP-targeted LNC1009 program | Yantai (Shandong), China | Dx + Tx | |
Lantheus | Commercial radiopharmaceutical company with legacy approved therapy and emerging therapeutic pipeline | North Billerica, MA, USA | Therapeutic | |
Life Molecular Imaging | Develops and commercialises molecular imaging agents for neurological diseases; portfolio includes Neuraceq (18F-florbetaben) for amyloid PET imaging in Alzheimer's disease diagnostics; expanding into tau and other neurodegenerative targets | Berlin, Germany | Diagnostic | |
LinqMed | Builds a Cu-64 drug discovery platform for theranostic radiopharmaceuticals targeting cancers with unmet need | Chiba, Japan | Dx + Tx | |
MDG Molecular Diagnostics | Dresden-based radiopharmacy network company and research partner in SNRT (Saxon Network for Radionuclide Theranostics) developing dual-modality radiotheranostics | Dresden, Germany | Dx + Tx | |
Mednovo Group | Developer of 177Lu-oxodotreotide injection (SSTR2-targeted) for GEP-NETs; Phase III clinical trial with first patient dosed August 2025; C-Ray Therapeutics as exclusive CRDMO partner | Suzhou, China | Therapeutic | |
MedTrace Pharma | Develops PET radiotracers for neuroinflammation and neurodegenerative diseases using proprietary 18F-labelled TSPO (translocator protein) ligands; advancing clinical imaging agents for brain inflammation detection | Copenhagen, Denmark | Diagnostic | |
MITRO Biotech | Chinese radiopharmaceutical developer with proprietary RDC pipeline targeting PSMA, FAP and other tumour antigens; building integrated development and manufacturing capabilities for radioligand therapies | Shanghai, China | Therapeutic | |
Modulation Therapeutics | Develops 225Ac-MTI-201, an MC1R-targeted alpha therapy in Phase 1 for metastatic uveal melanoma; also advancing MTI-301 and other MC1R-directed radioligands for melanoma and solid tumours; West Virginia University spinout | Morgantown, WV, USA | Therapeutic | |
Molecular Partners | Develops DARPin-based targeted alpha therapies using Pb-212, co-developing 10 programs with Orano Med (MP0712 DLL3→SCLC now FIH 2025) | Zurich-Schlieren, Switzerland | Therapeutic | |
Molecular Targeting Technologies | Small privately held biotech developing Evans-blue-enhanced (albumin-binding) radiotherapeutics; lead EBTATE (Lu-177) with long-acting SSTR2 targeting | West Chester, PA, USA | Dx + Tx | |
Monopar Therapeutics | uPAR-targeted antibody radioconjugate developer | Wilmette, IL, USA | Dx + Tx | |
Na'an Bio (Nanolattix) | ADC/RDC dual-track biotech using BioLattix platform; flagship radiopharma asset RT01 is a tissue-factor-targeting theranostic RDC (Zr-89/Lu-177/Ac-225) that dosed first patient in IIT February 2026; also developing bispecific RDC pipeline | Shanxi, China | Dx + Tx | |
Nami Therapeutics | Radiopharmaceutical nanoparticle company developing Ho-166 nanocarriers (XLNT-1) for targeted intraperitoneal delivery to ovarian cancer metastases | Storrs, CT, USA | Therapeutic | |
NanoMab Technology | Develops camelid single-domain antibody (sdAb/nanobody) radiopharmaceuticals as theranostic pairs for cancer precision medicine (imaging + therapy) | Borehamwood, Hertfordshire, UK | Dx + Tx | |
Navidea Biopharmaceuticals | NYSE-listed (NAVB) developer of Tc-99m tilmanocept (Lymphoseek), an FDA-approved CD206-targeted radiopharmaceutical for sentinel lymph node mapping in cancer surgery; expanding into CD206-targeted immunodiagnostics | Dublin, OH, USA | Diagnostic | |
Navigo Proteins | Develops Affilin®-scaffold radiotheranostics for cancer; GAIASO focuses specifically on female cancers (ovarian, cervical, breast) | Halle (Saale) (Navigo); Germany/Australia (GAIASO), Germany | Dx + Tx | |
New Radiomedicine Technology | Full value-chain radiopharma developer; Y-90 microspheres advanced clinical, but FAP-targeted 177Lu-NRT6020 is a genuinely early theranostic asset | Chengdu, China | Dx + Tx | |
Nihon Medi-Physics (NMP) | Leading Japanese radiopharmaceutical developer (Sumitomo Chemical / GE HealthCare JV); proprietary alphaSTARTZ platform: NMK89 (Zr-89 MUC5AC PET, FDA IND, FIH completed at BAMF Health) paired with NMT25 (Ac-225 therapeutic) for pancreatic cancer | Tokyo, Japan | Dx + Tx | |
Node Pharma | Preclinical radiopharmaceutical company developing first-in-class targeted alpha therapies for liver cancer and metastatic indications | Oslo, Norway | Therapeutic | |
Nordic Nanovector | Develops Betalutin (177Lu-lilotomab satetraxetan), a CD37-targeted antibody-radionuclide conjugate for non-Hodgkin lymphoma; Phase 2b PARADIGME trial ongoing; Oslo-listed clinical-stage radioimmunotherapy company | Oslo, Norway | Therapeutic | |
Norroy Biopharm | Develops RDC therapeutics with global IND filings: 177Lu-NYM032 in Phase I/II (enrolment complete) for renal cancer; additional renal and solid-tumour programmes; 5 FDA and 5 NMPA INDs accepted; dual US-China operations | China / USA | Dx + Tx | |
Novartis | Global radioligand therapy leader with approved Lu-177 products and next-generation alpha/beta pipeline | Basel, Switzerland | Therapeutic | |
NuclearMediX | Scalable 18F-SSTR-PET radiotracer platform (FETO tracer) to address the 50% supply shortage of SSTR diagnostics for neuroendocrine tumours | London (Imperial College White City), UK | Diagnostic | |
Nuclide Therapeutics | Develops ALDH1A1-targeted radiotheranostics using Lu-177/Ga-68 to detect and eliminate therapy-resistant cancers | London, UK | Dx + Tx | |
Nuclidium | Develops copper-based (Cu-61/Cu-67) theranostic radiopharmaceuticals targeting PSMA, SSTR2, and FAP for solid tumour oncology | Basel / Munich, Switzerland / Germany | Dx + Tx | |
NucliThera | R&D spinout developing targeted alpha/beta radioligand therapies for hematological cancers (lymphoma, leukemia) using Th-228-derived isotopes | Oslo, Norway | Therapeutic | |
NuView Life Sciences | Clinical-stage theranostic radiopharmaceutical company developing NV-VPAC1, a VPAC1 receptor-targeted platform pairing Cu-64 (PET diagnostic) with Cu-67 (therapeutic) for prostate, bladder, breast and other cancers | Park City, UT, USA | Dx + Tx | |
Oncodesign Precision Medicine | Biopharma developing radioligand therapy via the Promethe® platform using Affilin® vectors (collaboration with Navigo Proteins) | Dijon, France | Therapeutic | |
Oncoinvent | Develops Radspherin, an alpha-emitting Ra-224-loaded calcium carbonate microparticle for intraperitoneal treatment of peritoneal carcinomatosis from ovarian and colorectal cancers; Phase 2 trials ongoing in Europe | Oslo, Norway | Therapeutic | |
OncoOne | Develops FAP-targeted radioligands and small-molecule drug conjugates for solid tumours; proprietary FAP-binding scaffolds designed for improved tumour retention and theranostic pairing with diagnostic and therapeutic radionuclides | Vienna, Austria | Dx + Tx | |
OncoTherapy Science | TSE: 4564; develops OTSA101, an anti-FZD10 monoclonal antibody radioimmunotherapy (90Y/225Ac-labeled) for synovial sarcoma; first-in-human Synfrizz trial conducted; University of Tokyo spinout with oncology peptide vaccine platform | Kawasaki, Japan | Therapeutic | |
Orano Med | Lead-212 targeted alpha therapy developer and manufacturer | Paris / Bessines-sur-Gartempe, France | Therapeutic | |
PDRadiopharma | Discovers, develops, and commercializes peptide-based radiopharmaceuticals (RI-PDC) across multiple oncology targets using PeptiDream's PDPS platform | Tokyo, Japan | Dx + Tx | |
Pentixapharm | Clinical-stage and early-stage developer of CXCR4-targeted radiopharmaceuticals (PentixaTher/PentixaFor) and novel preclinical radionuclide-therapy programs | Berlin / Würzburg, Germany | Dx + Tx | |
Perseus Proteomics | Develops radiolabeled antibodies including PPMX-T002 (anti-CDH3 / P-cadherin) repositioned for 225Ac alpha radioimmunotherapy; University of Tokyo spinout with diagnostic radiopharmaceutical and antibody platform programmes | Tokyo, Japan | Dx + Tx | |
Perspective Therapeutics | Pb-212 alpha therapy developer with generator platform and theranostic imaging pairs | Seattle, WA / Coralville, IA, USA | Dx + Tx | |
Philogen | Develops FAP-targeting radioligand therapies (OncoFAP platform, 177Lu-OncoFAP-23) for solid tumors; Phase 1 trial (Theratri, NCT06640413) ongoing | Siena, Italy (Philogen); Otelfingen (Zurich), Switzerland (Philochem), Italy / Switzerland | Therapeutic | |
Photinia Biosciences | Preclinical radiopharmaceutical company focused on selectively targeting cancer cells and enabling deep tumor penetration | Bay Area, CA (inferred; HQ not publicly disclosed), USA | Therapeutic | |
Plus Therapeutics | Developer of locally delivered rhenium-186 nanoliposome radiotherapeutics for CNS cancers | Austin, TX, USA | Therapeutic | |
Precirix NV | Nanobody/VHH radiopharmaceutical company targeting HER2 and FAP | Brussels, Belgium | Therapeutic | |
PreTT | Pretargeted radioligand therapy (RLT) platform using monoclonal antibodies (mAbs) as targeting vectors for alpha-emitting payloads. | Copenhagen, Denmark | Therapeutic | |
Primo Biotechnology | Develops next-generation radioligand theranostics (RLT) targeting PSMA, FOLH1, and other tumor markers for solid cancers | Taipei, Taiwan | Dx + Tx | |
Q BioMed | Holder of legacy Sr-89 bone-palliation radiopharmaceutical brand lineage | New York / Chicago, USA | Therapeutic | |
QSAM Biosciences | Developer of CycloSam (Sm-153-DOTMP), a bone-targeting radiopharmaceutical for primary and metastatic bone cancers; FDA IND cleared; Telix Pharmaceuticals signed acquisition term sheet and $2M option fee (Nov 2023) | Austin, TX, USA | Therapeutic | |
R2PHARMA | Brazilian radiopharmaceutical developer focused on peptide receptor radionuclide therapy (PRRT) for neuroendocrine and other cancers; developing locally produced Lu-177-DOTATATE and novel radioligand formulations for Latin American markets | Sao Paulo, Brazil | Therapeutic | |
RadioMedix | Clinical-stage radiotheranostics developer and AlphaMedix originator/co-developer | Houston, TX, USA | Dx + Tx | |
Radiomer Therapeutics | Fannin-founded company developing targeted radiopharmaceuticals using the proprietary Raptamer targeting platform for theranostic radioligand therapy; lead programmes target established and first-in-class cancer antigens; launched from stealth May 2024 | Houston, TX, USA | Dx + Tx | |
RadioNano Therapeutics | Develops novel boron-containing inorganic nanoparticles for Boron Neutron Capture Therapy (BNCT) to overcome limitations of current BPA formulations | Kyoto, Japan | Therapeutic | |
Radionetics Oncology | Discovers and develops small-molecule non-peptide radioligands targeting GPCRs overexpressed on solid tumors using a proprietary platform | San Diego, CA, USA | Dx + Tx | |
Radiopharm Theranostics | Novel-target radiopharmaceutical developer across PD-L1, HER2, B7-H3, KLK3 and brain-metastasis targets | Sydney, Australia | Therapeutic | |
Ratio Therapeutics | Dual proprietary platform: Trillium™ (trifunctional small-molecule scaffold for PK modulation) and Macropa™ (best-in-class bifunctional Ac-225 chelator) | Boston, MA, USA | Dx + Tx | |
Rhine Pharma | Spinout from Telix/Heidelberg University Hospital developing a 99mTc/188Re-labelled PSMA-targeting theranostic pair (RHN001) leveraging generator-produced isotopes | Heidelberg, Germany | Dx + Tx | |
Roche | Large pharma entering Pb-212 pretargeted radioimmunotherapy | Basel / South San Francisco, Switzerland / USA | Therapeutic | |
Sanofi | Large pharma licensee of lead-212 SSTR alpha therapy | Paris, France | Therapeutic | |
Shiya Pharmaceutical | Shanghai-based developer of [99mTc]SY101, a PSMA-targeted SPECT/CT diagnostic imaging agent for prostate cancer; CDE clinical trial approval December 2023; reported as the first domestic Tc-99m PSMA imaging agent in China with Phase III plans | Shanghai, China | Diagnostic | |
Sinotau Pharmaceutical | China's leading theranostic radiopharmaceutical company with a broad pipeline; preclinical programs XTR015/XTR021/XTR024 alongside late-stage assets | Beijing, China | Dx + Tx | |
SK Biopharmaceuticals | Builds a preclinical RPT pipeline in-licensing and developing Ac-225-based radiopharmaceuticals for solid tumors | Seoul, South Korea | Dx + Tx | |
SmartNuclide | Nanobody/single-domain antibody (SRC) platform for theranostic radiopharmaceuticals; therapeutic RDC programs in preclinical development | Suzhou, China | Dx + Tx | |
SOFIE Biosciences | Developer and Phase 3 sponsor of [18F]FAPI-74, an FAP-targeted PET tracer for GI cancers; two Phase 3 trials active: FAPI-GO (gastroesophageal, first patient dosed Dec 2025) and FAPI-PRO (PDAC, first patient dosed Feb 2026); GE HealthCare licensing partner | Dulles, VA, USA | Diagnostic | |
Solve Therapeutics | Antibody/nanobody-based radionuclide therapeutics incorporating Cereius (Duke University spinout, acq. 2023) modular site-specific radiolabeling | San Diego, CA / Durham, NC, USA | Dx + Tx | |
Spago Nanomedical | STO: SPAGO; develops 177Lu-SN201 (Tumorad), a receptor-independent nanoparticle radioligand therapy exploiting the EPR effect for tumour targeting; Phase I/IIa ongoing; also developing SpagoPix MRI contrast agent | Lund, Sweden | Therapeutic | |
Starget Pharma | Israeli developer of somatostatin-based precision radioligands using an AI-driven peptide discovery platform; $18M Series A (Feb 2026); lead programme and breast/prostate cancer candidate entering clinical trials in Australia | Israel | Dx + Tx | |
Starpharma Holdings | ASX: SPL; develops DEP dendrimer-based radiotheranostics including a HER2 radiodiagnostic (89Zr) and radiotherapeutic (177Lu) programme; FDA-aligned first-in-human Phase 1 planned for H2 2026; primarily known for VivaGel and DEP drug delivery | Melbourne, Australia | Dx + Tx | |
Telix Pharmaceuticals | Commercial-stage theranostic company with Phase 3 therapeutic programmes in prostate, brain and kidney cancers | Melbourne, Australia | Dx + Tx | |
TetraKit Technologies | Platform radiopharma biotech developing universal radiolabeling chemistry (tetrazine click ligation) for rapid theranostic radiopharmaceuticals | Copenhagen, Denmark | Dx + Tx | |
Torpedo Pharmaceuticals | Radiotherapeutics subsidiary of Swiss Rockets developing Terbium-161-based radioligand therapies including 161Tb-PSMA for prostate cancer; discovery-stage programmes with academic and industrial partnerships; January 2026 deal with Alloy Therapeutics | Basel, Switzerland | Therapeutic | |
Trimt | Discovers and licenses next-generation radioligands for integrin-targeted theranostics, including an αvβ6-integrin therapeutic counterpart | Radeberg (near Dresden), Germany | Dx + Tx | |
TwoStep Therapeutics | Develops a modality-agnostic polyspecific integrin-binding peptide (PIP) tumor-targeting platform for drug conjugates, immunotherapy, and radioligand therapy | San Carlos, CA, USA | Dx + Tx | |
Vect-Horus | Designs BBB-crossing peptide/nanobody vectors (VECTrans®) for targeted delivery of radioisotopes to brain tumors and solid cancers | Marseille, France | Dx + Tx | |
VitsGen Therapeutics | Shandong-based developer of 177Lu-PSMA-VG01, a self-developed PSMA-targeted radioligand therapy for mCRPC; CDE IND accepted September 2025; also advancing preclinical 225Ac-PSMA-VG01 alpha programme | Shandong, China | Therapeutic | |
Xingrui Jingxuan (Fosun Pharma) | Dedicated radiopharma subsidiary of Fosun Pharma developing pan-tumour theranostic radiopharmaceuticals; lead asset SRT-007 (Ga-68/Lu-177 PSMA theranostic pair) in Phase I for mCRPC; Fudan University patent collaboration covering solid-tumour targeted radioligands | Chengdu, China | Dx + Tx | |
Y-mAbs Therapeutics | Antibody therapeutics company that advanced I-131-omburtamab radioimmunotherapy in pediatric/rare cancers | New York, NY, USA | Therapeutic | |
Yantai Dongcheng Pharmaceutical | Chinese radiopharmaceutical manufacturer and parent of Lannacheng spin-out | Yantai, China | Dx + Tx | |
Yunnan Baiyao (Yunhe Medicine) | Major Chinese pharma (SZSE: 000538) with radiopharma pipeline through Yunhe Medicine subsidiary: INR101 (PSMA PET diagnostic, Phase III prostate cancer), INR102 (therapeutic RLT, Phase I/IIa), INR301 (mAb, IND accepted); PSMA-P137 patent licensed from Peking University Cancer Hospital | Kunming, China | Dx + Tx | |
Z-Alpha Therapeutics | Proprietary At-211 (astatine-211) platform with novel labeling/linker technology, integrated global isotope supply, and a pipeline of targeted alpha therapies | San Diego, CA, USA | Dx + Tx | |
Zonsen PepLib Biotech | Develops peptide-radionuclide conjugate (PRC) radioligand therapies; lead asset licensed to Novartis in January 2026 ($50M upfront, worldwide rights); internally developed RLT pipeline beyond the out-licensed programme; 200+ staff across Zhuzhou and New Jersey | Zhuzhou, China | Therapeutic |
3B Pharmaceuticals
Develops peptide-targeted radionuclide therapeutics and FAP-targeting radioligands primarily through out-licensing to larger partners
Berlin, Germany
3D Medicines
Shanghai-listed biopharma (688435.SH) with RDC/radioligand pipeline including Lu-177-PSMA-3D1015 in clinical development for metastatic castration-resistant prostate cancer; primarily an ADC and immuno-oncology company expanding into radiopharmaceuticals
Shanghai, China
AB-RayBio
Early-stage developer of targeted radiopharmaceuticals with α- and β-nuclide programs; eight in-research pipelines including pan-solid-tumor programs
Hangzhou, China
Abdera Therapeutics
Engineers precision radiopharmaceuticals using its ROVEr™ antibody engineering platform to deliver alpha (Ac-225) or beta emitters against novel targets
South San Francisco, CA, USA
Ablaze Pharmaceuticals
GPC-3-targeted radioligand therapy for hepatocellular carcinoma (HCC) using novel peptide drug candidates; collaboration with BMS/PeptiDream
Shanghai / Greater China, China
ABSCINT
Develops anti-L1CAM monoclonal antibody radioconjugates for paediatric and adult solid tumours, including radiolabeled OTLC anti-L1CAM antibodies; spin-out from UCLouvain collaborating with SCK CEN on therapeutic radionuclide conjugation
Brussels, Belgium
AC Immune
Clinical-stage biopharma developing 18F-ACI-12589, the first-ever alpha-synuclein PET tracer with first-in-human data published in Nature Communications; wholly owned diagnostic for MSA, Parkinson's disease and other synucleinopathies
Lausanne, Switzerland
Acrotech Biopharma
Commercial oncology company holding US Zevalin radioimmunotherapy rights
East Windsor, NJ, USA
Actinium Pharmaceuticals
NYSE-listed company with a novel preclinical Ac-225 solid-tumor program (ATNM-400) targeting a non-PSMA antigen in prostate, NSCLC, and breast cancer
New York, NY, USA
Actithera
Precision radiopharmaceutical biotech translating covalent medicinal chemistry into next-generation radioligand therapies, with an isotope-agnostic approach
Cambridge, MA (co-HQ Oslo, Norway), USA/Norway
Advanced Innovative Partners (AIP)
Theranostic radiopharmaceutical developer with pipeline including AIP-201, AIP-105 (rare paediatric), AIP-301, and AIP-102 across oncology, infectious disease and rare disease; holds first accelerator-produced Ac-225 patent; also provides CRO services
Boynton Beach, FL, USA
AdvanCell
Lead-212 targeted alpha therapy developer
Melbourne, Australia
Affibody
Affibody molecule platform company developing HER2 radioligand therapy
Stockholm, Sweden
Akiram Therapeutics
Develops CD44v6-targeting radioimmunotherapy (177Lu-AKIR001) for solid tumors including head & neck and thyroid cancers; FIH Phase 1 initiated
Uppsala, Sweden
Aktis Oncology
Miniprotein Ac-225 radioconjugate developer for solid tumors
Boston, MA, USA
Alpha Fusion
Develops At-211-based Targeted Alpha Therapy (TAT) radiopharmaceuticals across multiple cancer indications
Osaka, Japan
Alpha-9 Oncology
MC1R-targeted radiopharmaceutical developer for melanoma and other cancers
Vancouver, BC / Boston, MA, Canada / USA
AlphaGen Therapeutics
Develops next-generation Pb-212 alpha radioligand therapies using proprietary AlphaDirect Pb-212 generator technology
Shanghai, China
Andarix Pharmaceuticals
Clinical-stage developer of Re-188-P2045 (Tozaride), a SSTR2-targeting peptide radiotherapy for neuroendocrine tumours and lung cancer, paired with 99mTc-P2045 diagnostic imaging agent; advancing through Phase 2
Somerville, MA, USA
APRINOIA Therapeutics
Clinical-stage company developing tau-targeted PET diagnostic tracers (18F-APN-1607/florzolotau) and therapeutic radiopharmaceuticals for neurodegenerative diseases and brain cancers; Phase 2/3 tau PET imaging studies ongoing globally
Taipei / Suzhou, Taiwan / China
Archeus Technologies
RPT company developing PSMA and other targeted radioconjugates
Madison, WI, USA
Ariceum Therapeutics
SSTR2 antagonist and PARP-targeted radiopharmaceutical developer
Berlin, Germany
Artbio
Lead-212 alpha radioligand therapy developer using AlphaDirect isotope isolation
Cambridge, MA, USA
AstraZeneca
Large pharma alpha-radioconjugate platform targeting PSMA, IGF-1R, EGFR/cMET and NTSR1
Cambridge / Hamilton, ON, UK / Canada
Atonco Pharma
At-211 antibody-conjugate (girentuximab × CA-IX) for non-muscle-invasive bladder cancer; FIH Phase 1 PERSEVERANCE EU trial authorized
Saint-Herblain (Nantes), France
Bayer
Commercial alpha-emitter franchise and next-generation Ac-225 oncology pipeline
Leverkusen, Germany
Beijing Quarkxia Technology
Chinese radionuclide therapeutic developer for bone metastases
Beijing, China
Bicycle Therapeutics
Develops Bicycle® Radioconjugates (BRC®) using proprietary bicyclic peptides carrying ²¹²Pb (alpha) for targeted radionuclide therapy
Cambridge, UK
Biokin Pharmaceutical (Baili Tianheng)
Shanghai-listed biopharma (688506.SH) expanding into radiopharmaceuticals with BL-ARC001 (Lu-177 RDC) in clinical development for prostate cancer; primarily known as a leading Chinese ADC developer with BMS partnership on cadonilimab-equivalent
Chengdu, China
Bivision Pharmaceuticals
Chinese PSMA-targeted radioligand therapy developer
Shanghai / Nanjing, China
Blue Earth Therapeutics
Develops an alpha-emitting radiohybrid PSMA-targeted therapeutic radiopharmaceutical (²²⁵Ac-rhPSMA-10.1) for prostate cancer
Oxford, UK
BoomRay
Academic spin-out (WuXi AppTec + Peking University Molecular Engineering) developing first-in-class covalent targeted radioligand therapies
Suzhou, China
Bristol Myers Squibb
Large pharma actinium-225 radiopharmaceutical platform via RayzeBio acquisition
Princeton, NJ / San Diego, CA, USA
C-Biomex
Korean developer of fluorine-18 PET imaging agents including 18F-FP-CIT for Parkinson's disease diagnosis and novel oncology tracers; holds KFDA approvals for multiple diagnostic radiopharmaceuticals
Seoul, South Korea
C-Ray Therapeutics
Chengdu-based CRDMO with own therapeutic pipeline: TRC003, a PSMA-targeted radioligand in Phase 1/2 for metastatic castration-resistant prostate cancer (NCT07567521, 90 patients, sites in China); alpha-emitting RDC programs
Chengdu, China
Cancer Targeted Technology (CTT)
PSMA-targeted theranostic developer: CTT1403 (177Lu radiotherapeutic, albumin-binding, Phase 1 complete at UCSF) paired with CTT1057 (18F PET diagnostic, Phase 1 complete); irreversible PSMA binding scaffold
Woodinville, WA, USA
CellBion
Korean PSMA radioligand developer
Seoul, South Korea
Cellectar Biosciences
Clinical-stage company with a phospholipid ether (PLE) platform; CLR 125 (Auger/I-125) in Phase 1b TNBC and CLR 225, an Ac-225 alpha emitter
Florham Park, NJ, USA
Chengdu Huasun Biotechnology
China domestic radioimmunotherapy manufacturer for hepatocellular carcinoma
Chengdu, China
Clarity Pharmaceuticals
Copper-64/copper-67 SAR theranostic radiopharmaceutical developer
Sydney, Australia
Convergent Therapeutics
PSMA-targeted alpha radioantibody developer
Cambridge, MA, USA
Curadel Pharma
Develops fluorescence-guided surgery and targeted radiopharmaceutical agents combining near-infrared fluorescent imaging with radioligand delivery for intraoperative tumour detection and treatment
Marlborough, MA, USA
Curasight
uPAR-targeted theranostics company developing uTREAT radiopharmaceutical therapy
Copenhagen, Denmark
Curium Pharma
Large nuclear medicine company with approved legacy therapies and Phase 3 PSMA therapy
Paris, France
CytoSite Bio
Granzyme B-targeted theranostic developer: CSB-321 PET diagnostic (Phase 1, validated in melanoma and NSCLC) paired with CSB-421 radiotherapeutic; Lantheus holds an option deal (March 2025) on the platform
Boston, MA, USA
Debiopharm
Swiss biopharma developing terbium-161-based radioligand therapies for cancer through its Nucleo-Oncology programme; partners with Paul Scherrer Institute and CERN/ISOLDE for Tb-161 production; advancing proprietary theranostic candidates
Lausanne, Switzerland
Defence Therapeutics
Canadian biotech (CSE: DTC) developing Accum-enhanced radio-immunoconjugates in collaboration with Canadian Nuclear Laboratories using Ac-225 and In-111 isotopes; radiopharmaceuticals are a top development priority alongside its ADC programme
Montreal, Canada
Diaprost
Develops h11B6, a humanised monoclonal antibody targeting hK2 (human kallikrein 2) as a radioimmunotherapy carrier for prostate cancer; paired diagnostic and therapeutic applications using different radionuclide payloads
Lund, Sweden
Dong Wha Pharmaceutical
Korean pharmaceutical company holding an approved Ho-166 locoregional radiotherapy product
Seoul, South Korea
DuChemBio
Korea's leading radiopharmaceutical manufacturer with ~80% of the domestic FDG market; approved diagnostics (68Ga-PSMA-11, 18F-FES for breast cancer) and expanding into therapeutic radioligands and CDMO services
Seoul, South Korea
Eli Lilly
Large pharma radiopharmaceutical division with POINT-origin Lu-177 and Ac-225 assets plus new collaborations
Indianapolis, IN, USA
Evergreen Theragnostics
Radiopharma CDMO and proprietary developer; built a GMP facility in NJ; lead diagnostic OCTEVY (EVG321, CCK2-targeting, SCLC) in Phase II
Springfield, NJ, USA
Faber Xintian
Develops 99mTc-H7ND, a world-first FAP-targeted SPECT/CT diagnostic radiopharmaceutical (Class 1 innovative drug); CDE clinical trial approval December 2023; Phase 1 initiated April 2024 at Fudan Zhongshan Hospital; strategic collaboration with HTA/Atom HighTech
Jiaxing, China
Foshan Radiomedical / Beijing Jiluntai
Chinese developer and manufacturer of Sm-153-EDTMP (samarium-153 lexidronam) and other therapeutic radiopharmaceuticals for bone pain palliation in metastatic cancer; one of China's established radiopharmaceutical producers
Foshan / Beijing, China
Fujifilm Toyama Chemical
Japan marketing authorization holder/commercial partner for Lutathera PRRT
Tokyo, Japan
Fulian Medicine
Radionuclide drug conjugate (RDC) developer with global R&D operations spanning China, Belgium, and Germany; more than 30% of staff based in Belgium; developing nanoparticle-based radioligand therapies for solid tumours
Beijing, China
Full-Life Technologies
Fully integrated radiotherapeutics company with an Ac-225 lead program in Phase I and multiple preclinical programs (SSTR2, c-MET, B7H3) in discovery
Suzhou / Shanghai, China (global)
FutureChem
Developing alpha-emitter radiopharmaceuticals alongside beta-emitter programs for prostate and other cancers
Seoul, South Korea
Fuzionaire Theranostics
Developer of novel FAPI (fibroblast activation protein inhibitor) radioligands for theranostic cancer applications; advancing FAP-targeted imaging and therapeutic agents through clinical development
San Diego, CA, USA
GlyTherix
Develops glypican-1 (GPC1)-targeted radioimmunotherapy for pancreatic and other GPC1-expressing cancers; lead programme uses radiolabeled anti-GPC1 antibodies with Lu-177 and other therapeutic radionuclides
Sydney, Australia
Grand Pharma
HK-listed biopharma with early own-pipeline radiopharma programs; GPN01530 (diagnostic FAP RDC, FIH just starting for diagnostic use)
Wuhan / Chengdu, China
Hexin Pharmaceuticals
Pioneer of dual-target radiopharmaceuticals simultaneously targeting integrin αvβ3 and CD13 receptor; first-in-class theranostic RDC platform
Chongqing / Beijing / Suzhou, China
HTA Co (Atom HighTech)
Major Chinese radiopharmaceutical developer and manufacturer under CNNC/CIRC with own clinical pipeline: F-18 Florastamin (Phase 3, prostate), Ga-68 DOTATATE (Phase 3, NETs), Lu-177 oxodotreotide (GEP-NETs); FutureChem collaboration on FC705 Lu-177 PSMA therapy; nationwide production and distribution network
Beijing, China
ImaginAb
Develops CD8-targeted ImmunoPET imaging agents (89Zr-Df-IAB22M2C/tozarotide) to visualise immune-cell infiltration in tumours; partnered with Bristol Myers Squibb and Roche for clinical imaging trials; lead agent in Phase 2
Inglewood, CA, USA
Immunome
Oncology biotech adding FAP-targeted radioligand therapy to its antibody and ADC pipeline; also advancing radiolabeled antibody programmes
Bothell, WA, USA
imuveo
Munich-based early-stage company developing next-generation PET tracers for immune-response imaging and future radioligand therapies targeting cancer; backed by the EXIST Transfer of Research programme and Technical University of Munich
Munich, Germany
Iodax Pharma
Novel PSAt-Ga radiolabeling technology (in-licensed from Theranostic Solutions, Copenhagen) allowing At-211, 131I, or 68Ga labeling
Switzerland, Switzerland
ITM Isotope Technologies Munich
Vertically integrated radiopharma biotech with a late-clinical lead (ITM-11, Phase 3/NDA pending) and early-stage novel programs
Garching / Munich, Germany
Jiangsu Hengrui Pharmaceuticals
Major Chinese pharma (SHA: 600276) with emerging radioligand therapy pipeline; developing proprietary RDC candidates including PSMA- and FAP-targeted radioligands; leveraging established oncology and clinical-trial infrastructure
Lianyungang, China
JingHe Biotech
Chinese developer of JH020002, a Lu-177 radioligand therapy for advanced prostate cancer currently in clinical trials (also registered under Bivision Pharmaceuticals in the US); early-stage RDC pipeline
China
Johnson & Johnson
Large pharma with two Ac-225 prostate cancer radiopharmaceutical programmes
New Brunswick, NJ, USA
Jubilant Pharmova
Large Indian pharma group with a proprietary radiopharma therapeutic pipeline including FAPI tracers in preclinical development and I-131 mIBG
Noida, India
Jubilant Radiopharma
Nuclear medicine company manufacturing and commercializing diagnostic and therapeutic radiopharmaceuticals
Kirkland, QC / Noida, Canada / India
Kelun-Biotech
Large-cap ADC company expanding into RDC; SKB107 (small-molecule RDC for bone metastases) is its first RDC program in Phase I as of Aug 2025
Chengdu (Sichuan), China
Lannacheng Biotechnology
Radiopharmaceutical spin-out from Dongcheng (largest listed radiopharmaceutical company); Lu-177 PSMA in Phase II; FAP-targeted LNC1009 program
Yantai (Shandong), China
Lantheus
Commercial radiopharmaceutical company with legacy approved therapy and emerging therapeutic pipeline
North Billerica, MA, USA
Life Molecular Imaging
Develops and commercialises molecular imaging agents for neurological diseases; portfolio includes Neuraceq (18F-florbetaben) for amyloid PET imaging in Alzheimer's disease diagnostics; expanding into tau and other neurodegenerative targets
Berlin, Germany
LinqMed
Builds a Cu-64 drug discovery platform for theranostic radiopharmaceuticals targeting cancers with unmet need
Chiba, Japan
MDG Molecular Diagnostics
Dresden-based radiopharmacy network company and research partner in SNRT (Saxon Network for Radionuclide Theranostics) developing dual-modality radiotheranostics
Dresden, Germany
Mednovo Group
Developer of 177Lu-oxodotreotide injection (SSTR2-targeted) for GEP-NETs; Phase III clinical trial with first patient dosed August 2025; C-Ray Therapeutics as exclusive CRDMO partner
Suzhou, China
MedTrace Pharma
Develops PET radiotracers for neuroinflammation and neurodegenerative diseases using proprietary 18F-labelled TSPO (translocator protein) ligands; advancing clinical imaging agents for brain inflammation detection
Copenhagen, Denmark
MITRO Biotech
Chinese radiopharmaceutical developer with proprietary RDC pipeline targeting PSMA, FAP and other tumour antigens; building integrated development and manufacturing capabilities for radioligand therapies
Shanghai, China
Modulation Therapeutics
Develops 225Ac-MTI-201, an MC1R-targeted alpha therapy in Phase 1 for metastatic uveal melanoma; also advancing MTI-301 and other MC1R-directed radioligands for melanoma and solid tumours; West Virginia University spinout
Morgantown, WV, USA
Molecular Partners
Develops DARPin-based targeted alpha therapies using Pb-212, co-developing 10 programs with Orano Med (MP0712 DLL3→SCLC now FIH 2025)
Zurich-Schlieren, Switzerland
Molecular Targeting Technologies
Small privately held biotech developing Evans-blue-enhanced (albumin-binding) radiotherapeutics; lead EBTATE (Lu-177) with long-acting SSTR2 targeting
West Chester, PA, USA
Monopar Therapeutics
uPAR-targeted antibody radioconjugate developer
Wilmette, IL, USA
Na'an Bio (Nanolattix)
ADC/RDC dual-track biotech using BioLattix platform; flagship radiopharma asset RT01 is a tissue-factor-targeting theranostic RDC (Zr-89/Lu-177/Ac-225) that dosed first patient in IIT February 2026; also developing bispecific RDC pipeline
Shanxi, China
Nami Therapeutics
Radiopharmaceutical nanoparticle company developing Ho-166 nanocarriers (XLNT-1) for targeted intraperitoneal delivery to ovarian cancer metastases
Storrs, CT, USA
NanoMab Technology
Develops camelid single-domain antibody (sdAb/nanobody) radiopharmaceuticals as theranostic pairs for cancer precision medicine (imaging + therapy)
Borehamwood, Hertfordshire, UK
Navidea Biopharmaceuticals
NYSE-listed (NAVB) developer of Tc-99m tilmanocept (Lymphoseek), an FDA-approved CD206-targeted radiopharmaceutical for sentinel lymph node mapping in cancer surgery; expanding into CD206-targeted immunodiagnostics
Dublin, OH, USA
Navigo Proteins
Develops Affilin®-scaffold radiotheranostics for cancer; GAIASO focuses specifically on female cancers (ovarian, cervical, breast)
Halle (Saale) (Navigo); Germany/Australia (GAIASO), Germany
New Radiomedicine Technology
Full value-chain radiopharma developer; Y-90 microspheres advanced clinical, but FAP-targeted 177Lu-NRT6020 is a genuinely early theranostic asset
Chengdu, China
Nihon Medi-Physics (NMP)
Leading Japanese radiopharmaceutical developer (Sumitomo Chemical / GE HealthCare JV); proprietary alphaSTARTZ platform: NMK89 (Zr-89 MUC5AC PET, FDA IND, FIH completed at BAMF Health) paired with NMT25 (Ac-225 therapeutic) for pancreatic cancer
Tokyo, Japan
Node Pharma
Preclinical radiopharmaceutical company developing first-in-class targeted alpha therapies for liver cancer and metastatic indications
Oslo, Norway
Nordic Nanovector
Develops Betalutin (177Lu-lilotomab satetraxetan), a CD37-targeted antibody-radionuclide conjugate for non-Hodgkin lymphoma; Phase 2b PARADIGME trial ongoing; Oslo-listed clinical-stage radioimmunotherapy company
Oslo, Norway
Norroy Biopharm
Develops RDC therapeutics with global IND filings: 177Lu-NYM032 in Phase I/II (enrolment complete) for renal cancer; additional renal and solid-tumour programmes; 5 FDA and 5 NMPA INDs accepted; dual US-China operations
China / USA
Novartis
Global radioligand therapy leader with approved Lu-177 products and next-generation alpha/beta pipeline
Basel, Switzerland
NuclearMediX
Scalable 18F-SSTR-PET radiotracer platform (FETO tracer) to address the 50% supply shortage of SSTR diagnostics for neuroendocrine tumours
London (Imperial College White City), UK
Nuclide Therapeutics
Develops ALDH1A1-targeted radiotheranostics using Lu-177/Ga-68 to detect and eliminate therapy-resistant cancers
London, UK
Nuclidium
Develops copper-based (Cu-61/Cu-67) theranostic radiopharmaceuticals targeting PSMA, SSTR2, and FAP for solid tumour oncology
Basel / Munich, Switzerland / Germany
NucliThera
R&D spinout developing targeted alpha/beta radioligand therapies for hematological cancers (lymphoma, leukemia) using Th-228-derived isotopes
Oslo, Norway
NuView Life Sciences
Clinical-stage theranostic radiopharmaceutical company developing NV-VPAC1, a VPAC1 receptor-targeted platform pairing Cu-64 (PET diagnostic) with Cu-67 (therapeutic) for prostate, bladder, breast and other cancers
Park City, UT, USA
Oncodesign Precision Medicine
Biopharma developing radioligand therapy via the Promethe® platform using Affilin® vectors (collaboration with Navigo Proteins)
Dijon, France
Oncoinvent
Develops Radspherin, an alpha-emitting Ra-224-loaded calcium carbonate microparticle for intraperitoneal treatment of peritoneal carcinomatosis from ovarian and colorectal cancers; Phase 2 trials ongoing in Europe
Oslo, Norway
OncoOne
Develops FAP-targeted radioligands and small-molecule drug conjugates for solid tumours; proprietary FAP-binding scaffolds designed for improved tumour retention and theranostic pairing with diagnostic and therapeutic radionuclides
Vienna, Austria
OncoTherapy Science
TSE: 4564; develops OTSA101, an anti-FZD10 monoclonal antibody radioimmunotherapy (90Y/225Ac-labeled) for synovial sarcoma; first-in-human Synfrizz trial conducted; University of Tokyo spinout with oncology peptide vaccine platform
Kawasaki, Japan
Orano Med
Lead-212 targeted alpha therapy developer and manufacturer
Paris / Bessines-sur-Gartempe, France
PDRadiopharma
Discovers, develops, and commercializes peptide-based radiopharmaceuticals (RI-PDC) across multiple oncology targets using PeptiDream's PDPS platform
Tokyo, Japan
Pentixapharm
Clinical-stage and early-stage developer of CXCR4-targeted radiopharmaceuticals (PentixaTher/PentixaFor) and novel preclinical radionuclide-therapy programs
Berlin / Würzburg, Germany
Perseus Proteomics
Develops radiolabeled antibodies including PPMX-T002 (anti-CDH3 / P-cadherin) repositioned for 225Ac alpha radioimmunotherapy; University of Tokyo spinout with diagnostic radiopharmaceutical and antibody platform programmes
Tokyo, Japan
Perspective Therapeutics
Pb-212 alpha therapy developer with generator platform and theranostic imaging pairs
Seattle, WA / Coralville, IA, USA
Philogen
Develops FAP-targeting radioligand therapies (OncoFAP platform, 177Lu-OncoFAP-23) for solid tumors; Phase 1 trial (Theratri, NCT06640413) ongoing
Siena, Italy (Philogen); Otelfingen (Zurich), Switzerland (Philochem), Italy / Switzerland
Photinia Biosciences
Preclinical radiopharmaceutical company focused on selectively targeting cancer cells and enabling deep tumor penetration
Bay Area, CA (inferred; HQ not publicly disclosed), USA
Plus Therapeutics
Developer of locally delivered rhenium-186 nanoliposome radiotherapeutics for CNS cancers
Austin, TX, USA
Precirix NV
Nanobody/VHH radiopharmaceutical company targeting HER2 and FAP
Brussels, Belgium
PreTT
Pretargeted radioligand therapy (RLT) platform using monoclonal antibodies (mAbs) as targeting vectors for alpha-emitting payloads.
Copenhagen, Denmark
Primo Biotechnology
Develops next-generation radioligand theranostics (RLT) targeting PSMA, FOLH1, and other tumor markers for solid cancers
Taipei, Taiwan
Q BioMed
Holder of legacy Sr-89 bone-palliation radiopharmaceutical brand lineage
New York / Chicago, USA
QSAM Biosciences
Developer of CycloSam (Sm-153-DOTMP), a bone-targeting radiopharmaceutical for primary and metastatic bone cancers; FDA IND cleared; Telix Pharmaceuticals signed acquisition term sheet and $2M option fee (Nov 2023)
Austin, TX, USA
R2PHARMA
Brazilian radiopharmaceutical developer focused on peptide receptor radionuclide therapy (PRRT) for neuroendocrine and other cancers; developing locally produced Lu-177-DOTATATE and novel radioligand formulations for Latin American markets
Sao Paulo, Brazil
RadioMedix
Clinical-stage radiotheranostics developer and AlphaMedix originator/co-developer
Houston, TX, USA
Radiomer Therapeutics
Fannin-founded company developing targeted radiopharmaceuticals using the proprietary Raptamer targeting platform for theranostic radioligand therapy; lead programmes target established and first-in-class cancer antigens; launched from stealth May 2024
Houston, TX, USA
RadioNano Therapeutics
Develops novel boron-containing inorganic nanoparticles for Boron Neutron Capture Therapy (BNCT) to overcome limitations of current BPA formulations
Kyoto, Japan
Radionetics Oncology
Discovers and develops small-molecule non-peptide radioligands targeting GPCRs overexpressed on solid tumors using a proprietary platform
San Diego, CA, USA
Radiopharm Theranostics
Novel-target radiopharmaceutical developer across PD-L1, HER2, B7-H3, KLK3 and brain-metastasis targets
Sydney, Australia
Ratio Therapeutics
Dual proprietary platform: Trillium™ (trifunctional small-molecule scaffold for PK modulation) and Macropa™ (best-in-class bifunctional Ac-225 chelator)
Boston, MA, USA
Rhine Pharma
Spinout from Telix/Heidelberg University Hospital developing a 99mTc/188Re-labelled PSMA-targeting theranostic pair (RHN001) leveraging generator-produced isotopes
Heidelberg, Germany
Roche
Large pharma entering Pb-212 pretargeted radioimmunotherapy
Basel / South San Francisco, Switzerland / USA
Sanofi
Large pharma licensee of lead-212 SSTR alpha therapy
Paris, France
Shiya Pharmaceutical
Shanghai-based developer of [99mTc]SY101, a PSMA-targeted SPECT/CT diagnostic imaging agent for prostate cancer; CDE clinical trial approval December 2023; reported as the first domestic Tc-99m PSMA imaging agent in China with Phase III plans
Shanghai, China
Sinotau Pharmaceutical
China's leading theranostic radiopharmaceutical company with a broad pipeline; preclinical programs XTR015/XTR021/XTR024 alongside late-stage assets
Beijing, China
SK Biopharmaceuticals
Builds a preclinical RPT pipeline in-licensing and developing Ac-225-based radiopharmaceuticals for solid tumors
Seoul, South Korea
SmartNuclide
Nanobody/single-domain antibody (SRC) platform for theranostic radiopharmaceuticals; therapeutic RDC programs in preclinical development
Suzhou, China
SOFIE Biosciences
Developer and Phase 3 sponsor of [18F]FAPI-74, an FAP-targeted PET tracer for GI cancers; two Phase 3 trials active: FAPI-GO (gastroesophageal, first patient dosed Dec 2025) and FAPI-PRO (PDAC, first patient dosed Feb 2026); GE HealthCare licensing partner
Dulles, VA, USA
Solve Therapeutics
Antibody/nanobody-based radionuclide therapeutics incorporating Cereius (Duke University spinout, acq. 2023) modular site-specific radiolabeling
San Diego, CA / Durham, NC, USA
Spago Nanomedical
STO: SPAGO; develops 177Lu-SN201 (Tumorad), a receptor-independent nanoparticle radioligand therapy exploiting the EPR effect for tumour targeting; Phase I/IIa ongoing; also developing SpagoPix MRI contrast agent
Lund, Sweden
Starget Pharma
Israeli developer of somatostatin-based precision radioligands using an AI-driven peptide discovery platform; $18M Series A (Feb 2026); lead programme and breast/prostate cancer candidate entering clinical trials in Australia
Israel
Starpharma Holdings
ASX: SPL; develops DEP dendrimer-based radiotheranostics including a HER2 radiodiagnostic (89Zr) and radiotherapeutic (177Lu) programme; FDA-aligned first-in-human Phase 1 planned for H2 2026; primarily known for VivaGel and DEP drug delivery
Melbourne, Australia
Telix Pharmaceuticals
Commercial-stage theranostic company with Phase 3 therapeutic programmes in prostate, brain and kidney cancers
Melbourne, Australia
TetraKit Technologies
Platform radiopharma biotech developing universal radiolabeling chemistry (tetrazine click ligation) for rapid theranostic radiopharmaceuticals
Copenhagen, Denmark
Torpedo Pharmaceuticals
Radiotherapeutics subsidiary of Swiss Rockets developing Terbium-161-based radioligand therapies including 161Tb-PSMA for prostate cancer; discovery-stage programmes with academic and industrial partnerships; January 2026 deal with Alloy Therapeutics
Basel, Switzerland
Trimt
Discovers and licenses next-generation radioligands for integrin-targeted theranostics, including an αvβ6-integrin therapeutic counterpart
Radeberg (near Dresden), Germany
TwoStep Therapeutics
Develops a modality-agnostic polyspecific integrin-binding peptide (PIP) tumor-targeting platform for drug conjugates, immunotherapy, and radioligand therapy
San Carlos, CA, USA
Vect-Horus
Designs BBB-crossing peptide/nanobody vectors (VECTrans®) for targeted delivery of radioisotopes to brain tumors and solid cancers
Marseille, France
VitsGen Therapeutics
Shandong-based developer of 177Lu-PSMA-VG01, a self-developed PSMA-targeted radioligand therapy for mCRPC; CDE IND accepted September 2025; also advancing preclinical 225Ac-PSMA-VG01 alpha programme
Shandong, China
Xingrui Jingxuan (Fosun Pharma)
Dedicated radiopharma subsidiary of Fosun Pharma developing pan-tumour theranostic radiopharmaceuticals; lead asset SRT-007 (Ga-68/Lu-177 PSMA theranostic pair) in Phase I for mCRPC; Fudan University patent collaboration covering solid-tumour targeted radioligands
Chengdu, China
Y-mAbs Therapeutics
Antibody therapeutics company that advanced I-131-omburtamab radioimmunotherapy in pediatric/rare cancers
New York, NY, USA
Yantai Dongcheng Pharmaceutical
Chinese radiopharmaceutical manufacturer and parent of Lannacheng spin-out
Yantai, China
Yunnan Baiyao (Yunhe Medicine)
Major Chinese pharma (SZSE: 000538) with radiopharma pipeline through Yunhe Medicine subsidiary: INR101 (PSMA PET diagnostic, Phase III prostate cancer), INR102 (therapeutic RLT, Phase I/IIa), INR301 (mAb, IND accepted); PSMA-P137 patent licensed from Peking University Cancer Hospital
Kunming, China
Z-Alpha Therapeutics
Proprietary At-211 (astatine-211) platform with novel labeling/linker technology, integrated global isotope supply, and a pipeline of targeted alpha therapies
San Diego, CA, USA
Zonsen PepLib Biotech
Develops peptide-radionuclide conjugate (PRC) radioligand therapies; lead asset licensed to Novartis in January 2026 ($50M upfront, worldwide rights); internally developed RLT pipeline beyond the out-licensed programme; 200+ staff across Zhuzhou and New Jersey
Zhuzhou, China
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About this directory
Compiled and maintained by ProGen Search
ProGen Search is an executive search firm specialising in radiopharmaceutical, CDMO, and biotech leadership hiring.
Building or scaling one of the companies on this list? Every entry competes for the same scarce operator-grade leadership: a Head of CMC who has run a radioactive process, a VP of Quality with an FDA inspection behind them, a CSO who has actually shipped a radioligand. That market is where ProGen Search works.
ProGen Search Limited, Ground Floor, Techno Centre, Station Road, Horsforth, Leeds, LS18 5BJ. © 2026. For informational purposes only; not investment, legal or medical advice. Compiled from public sources as of 2026 and may have changed.